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Tumour Site-Specific Resources

Uterine (Unscheduled Bleeding)

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Key Areas

  • Screening and Prevention
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Unscheduled Vaginal Bleeding

Unscheduled vaginal bleeding is a common symptom of many benign gynaecological conditions and is often reported in patients taking HRT or hormonal contraception.  

Distinguishing between expected vaginal bleeding and an underlying issue can be challenging. 

Understanding what bleeding patterns are normal for these patients is crucial to prevent delayed diagnosis of a gynaecological malignancy.

You will find some resources below to support your clincal practice in Primary Care.

the torso and legs of an individual sat on an examination table

Unscheduled Vaginal Bleeding: When to Investigate in Primary Care

Unscheduled vaginal bleeding can be a key indicator of underlying conditions, including cancer. GatewayC’s Cancer Key provides practical guidance for primary care professionals on when to investigate and refer.

Stay informed and support early diagnosis—explore the resource here.

a screenshot of the uterine cancer course

Unscheduled Vaginal Bleeding: What You Need to Know

Unscheduled vaginal bleeding can be an important clinical sign that requires timely investigation. This infographic from GatewayC provides a clear, practical guide for primary care professionals on assessing and managing patients presenting with this symptom. Download it now to support faster recognition and appropriate referral pathways.

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Management of unscheduled bleeding on hormone replacement therapy (HRT)

Unscheduled bleeding while on hormone replacement therapy (HRT) can raise important clinical questions. The British Menopause Society (BMS) guideline provides clear, evidence-based recommendations to help clinicians assess, investigate, and manage this symptom effectively. Explore the full guidance here to support best practice in patient care.

This joint guideline has been prepared on behalf of the British Menopause Society, in partnership with the British Society of Gynaecological Endoscopy, British Gynaecological Cancer Society, Faculty of Sexual & Reproductive Healthcare, Getting It Right First Time (GIRFT), Royal College of General Practitioners and the Royal College of Obstetricians & Gynaecologists.

 

a female patient sat on an examination table, and a male doctor listening to what she is saying

Managing Unscheduled Bleeding on HRT

Unscheduled bleeding during hormone replacement therapy can be challenging to manage. This concise summary from Getting It Right First Time (GIRFT) outlines practical steps for assessment, investigation, and referral, supporting clinicians to deliver safe and effective care. Access the guide now to ensure best practice in managing this common presentation.

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